Stem Cell Treatment Modalities

Updated: Jan 7, 2020

Stem cell sources that have the potential to be used in medical treatments can be examined in many different groups. Stem cells can be used autologously (from the individual's own body) or allogeneically from another HLA-matched donor (from twins, parents, siblings, relatives and non-relatives). To summarize;

1- Stem cells isolated from cord blood (allogeneic)

2- Hematopoietic and/or mesenchymal stem cells (allogenic or autologous) isolated from bone marrow

3- Autologous mesenchymal stem cells derived from adipose tissue

4- Autologous hematopoietic stem cells derived from peripheral blood using the apheresis technique. Stem cells circulate in small amounts in total blood. However, it is expensive and laborious to use this whole blood as a stem cell source.

5- Fibroblast stem cells are oligopotent stem cells derived from subcutaneous connective tissue. Usually, the tissue behind the ear is used as a source. The proliferation of autologous fibroblasts by culturing in PRP (Platelet Rich Plasma) containing media can increase both the number and quality of cells. It is used for dermatocosmetic purposes especially in the treatment of skin defects.

6- Mixed-type concentrated fluid derived from bone marrow and containing stem cells "autologous bone marrow aspirate concentrate (BMAC)" or

bone marrow-derived mononuclear cell suspension "bone marrow mononuclear cells"

7- Adipose-derived stromal vascular fraction (fat-derived stromal vascular fraction) is a mixed type of concentrated fluid that is derived from adipose tissue and contains stem cells