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The Priapus Shot® (P-Shot)

 intracavernosal injection of   

platelet-rich plasma (PRP)

Platelet Rich Plasma (PRP) has become extremely popular over the last 5 years within aesthetic medicine. PRP has been used for many years in cardiac surgery, plastic surgery,  gynecology and orthopaedic surgery. More recently the potential benefits from PRP in erectile dysfunction have also started to be realised.


PRP is in the category of regenerative autologous treatments, which means it comes from your own blood and can stimulate cellular regeneration and tissue repair. Platelets are one of the cells in our blood and when activated, they can release growth factors and other proteins.  The effectiveness of PRP is dependent upon the release of specific growth factors from the alpha granules found in platelets. The alpha granules are responsible for releasing platelet derived growth factor (PDGF), transforming growth factor (TGF), vascular endothelial growth factor (VEGF), epidermal growth factor (EGF) and insulin-like growth factor (ILGF). These have all been shown to have specific positive effects on stem cells.   

The Priapus Shot® (P-Shot) is an office based non-surgical procedure for erectile dysfunction designed to deliver lasting improvements in sexual performance to men. Until recently, commonly available treatment options for erectile dysfunction have included over the counter vitamins and supplements, prescription medications, and surgical implants. The Priapus Shot® represents an alternative to supplements, and prescribed medications that works by harnessing your own body’s natural healing and repair capabilities to revitalize aging and damaged tissue.

Intracavernosal penile PRP process is called P-Shot®. The name P-Shot® is actually a shortened version for the Priapus Shot®. It was coined by Dr. Charles Runels after he first injected his own penis. He felt that Priapus, the Greek god of male regenerative power, perfectly represented what he was trying to achieve.

During the P-Shot procedure, the patient’s blood is drawn and the PRP is extracted using a centrifuge designed specifically for the purposes of separating the platelet-rich plasma from the rest of the blood. Priapus Shot® (P-Shot), is a safe, natural, non-surgical procedure that incorporates the harvesting and injection of one’s own plasma enriched growth factors or PRP into specific areas of the penis to treat erectile dysfunction.

The Priapus Shot® (P-Shot) procedure begins with a localized numbing agent applied to the penis. While the numbing agent takes effect, your UZ Clinic physician will draw a small volume of blood from your arm and place it in a device called a centrifuge device that spins down the blood to separate the platelets and growth factors from the rest of the blood components. The result is highly concentrated platelet rich plasma (PRP) that is then carefully injected into the shaft & into the head of the penis. Once injected, these blood-derived growth factors ignite the body’s unique tissue renewal process resulting in the type of firmer more reliable you experienced in your younger years. There is no recovery time and the results are almost immediate in some men. Full results appear in 2-3 months.


FDA approved PRP kits

Official procedure


45 minutes

No pain,

numbing cream on the skin

Minor potential side effects

Stronger & Firmer


Increased sensitivity in the penis

Increased sexual desire and pleasure

Sexual activity the same day

Results occur 4 weeks after procedure

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